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OPEN ENROLLMENT
Pilot Study of Add-On Fycompa (perampanel) Treatment for Catamenial Epilepsy

The procedures of this study include clinical measurements to assess seizure frequency, a questionnaire to determine the risk of hurting yourself, as well as the collection of blood and urine for a…

Investigator
Katherine Zarroli
IRB Number
IRB202102694
Location
Jacksonville

OPEN ENROLLMENT
Parallel-Group Study to Assess the Efficacy and Safety of Staccato Alprazolam in Study Participants 12 Years of Age and Older with Stereotypical Prolonged Seizures

Study EP0162 is a double-blind, randomized, placebo-controlled, multi-center, parallel-group, Phase 3 study to investigate the efficacy and safety of Staccato alprazolam in an outpatient setting in…

Investigator
Ramon Bautista, Suparna Krishnaiengar, Katherine Zarroli
IRB Number
WIRB20216831
Ages
12 Years
Sexes
All
Location
Jacksonville

OPEN ENROLLMENT
Safety and Therapeutic Measures of Transcranial Cathodal Direct Current Stimulation (tDCS) in Patients with Refractory Focal Epilepsy

The purpose of this research is to learn more about Transcranial Cathodal Direct Current Stimulation (tDCS) and to see if it can help reduce the frequency of seizures in both…

Investigator
Ramon Bautista, Suparna Krishnaiengar, Katherine Zarroli
IRB Number
WIRB20212642
Location
Jacksonville

OPEN ENROLLMENT
The SMILE 3 Initiative: Improving the well-being of persons with epilepsy

The purpose of this study is to see whether incorporating services that help patients with epilepsy learn about stress management will improve their overall well-being….

Investigator
Ramon Bautista
IRB Number
IRB202200383
Ages
18 Years – 88 Years
Sexes
All
Location
Jacksonville

An Outpatient Physical Therapy and Golf Program Designed for Individuals with Movement Disorders

The importance of physical activity for individuals with movement disorders, including Parkinson disease and Essential tremor, has been established. Barriers including patient engagement continue to…

Investigator
Michael Pulley
IRB Number
IRB202202232
Location
Jacksonville

Radicava (Edaravone) Biomarker Study

Radicava (Edaravone) Biomarker Study in Participants with Amyotrophic Lateral Sclerosis Optional DNA Sample…

Investigator
Katherine Zarroli
IRB Number
CED000000235
Location
Jacksonville

A randomized, double-blind, placebo-controlled study to investigate the efficacy and safety of carisbamate (ykp509) as adjunctive treatment forseizures associated with lennox-gastaut syndrome in children and adults, with optional open-label extension (20225661)

A randomized, double-blind, placebo-controlled study to investigate the efficacy and safety of carisbamate (ykp509) as adjunctive treatment forseizures associated with lennox-gastaut syndrome in…

Investigator
Ramon Bautista
IRB Number
IRB202102694
Location
Jacksonville

A Phase 2, Randomized, Double-Blind, Placebo-Controlled, Dose Range Finding Clinical Trial to Evaluate the Tolerability, Safety, and Efficacy of PRAX-944 in the Treatment of Adults with Essential Tremor (20214448)

A Phase 2, Randomized, Double-Blind, Placebo-Controlled, Dose Range Finding Clinical Trial to Evaluate the Tolerability, Safety, and Efficacy of PRAX-944 in the Treatment of Adults with Essential…

Investigator
Joseph Legacy
IRB Number
1329062
Location
Jacksonville

A Phase 2 Trial to Investigate the Efficacy, Safety, and Tolerability of Efgartigimod PH20 SC in Adult Patients with Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) (20202174)

A Phase 2 Trial to Investigate the Efficacy, Safety, and Tolerability of Efgartigimod PH20 SC in Adult Patients with Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) (20202174)…

Investigator
Michael Pulley
IRB Number
1289306
Location
Jacksonville

Long-Term, Observational, Registry of Patients With Generalized Myasthenia Gravis Who Have Received Treatment With Complement C5 Inhibition Therapies (20193186)

Long-Term, Observational, Registry of Patients With Generalized Myasthenia Gravis Who Have Received Treatment With Complement C5 Inhibition Therapies (20193186)…

Investigator
Michael Pulley
IRB Number
1295785
Location
Jacksonville

Open-label Extension of the ARGX-113-1802 Trial to Investigate the Long-term Safety, Tolerability, and Efficacy of Efgartigimod PH20 SC in Patients with Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) (20203748)

Open-label Extension of the ARGX-113-1802 Trial to Investigate the Long-term Safety, Tolerability, and Efficacy of Efgartigimod PH20 SC in Patients with Chronic Inflammatory Demyelinating…

Investigator
Michael Pulley
IRB Number
1299632
Location
Jacksonville

A phase 3, multi-center, double-blind, randomized, placebo-controlled trial to evaluate the efficacy and safety of reldesemtiv in patients with amyotrophic lateral sclerosis (als) (20211633)

A phase 3, multi-center, double-blind, randomized, placebo-controlled trial to evaluate the efficacy and safety of reldesemtiv in patients with amyotrophic lateral sclerosis (als) (20211633)…

Investigator
Michael Pulley
IRB Number
1313008
Location
Jacksonville

A phase III, randomized, double-blind, placebo-controlled, multicenter study to evaluate efficacy, safety, pharmacokinetics, and pharmacodynamics of satralizumab in patients with generalized myasthenia gravis (20210645)

A phase III, randomized, double-blind, placebo-controlled, multicenter study to evaluate efficacy, safety, pharmacokinetics, and pharmacodynamics of satralizumab in patients with generalized…

Investigator
Michael Pulley
IRB Number
1320377
Location
Jacksonville

A Phase 3, Open-Label Extension of COURAGE-ALS (CY 5031) (20225090)

A Phase 3, Open-Label Extension of COURAGE-ALS (CY 5031) (20225090)…

Investigator
Michael Pulley
IRB Number
1342397
Location
Jacksonville

A multicenter, randomized, double-blind, parallel-group, placebo-controlled variable treatment duration study evaluating the efficacy and safety of Siponimod (BAF312) in patients with secondary progressive multiple sclerosis (20130508)

A multicenter, randomized, double-blind, parallel-group, placebo-controlled variable treatment duration study evaluating the efficacy and safety of Siponimod (BAF312) in patients with secondary…

Investigator
Scott Silliman
IRB Number
1141678
Location
Jacksonville

A Multicenter, Global, Observational Study to Collect Information on Safety and to Document the Drug Utilization of Tecfidera™ (Dimethyl Fumarate)

When Used in Routine Medical Practice in the Treatment of Multiple Sclerosis (ESTEEM) (20131917)…

Investigator
Scott Silliman
IRB Number
1155339
Location
Jacksonville

Safety and therapeutic measures of transcranial cathodal direct current stimulation (tdcs) in patients with refractory focal epilepsy (20212642)

Safety and therapeutic measures of transcranial cathodal direct current stimulation (tdcs) in patients with refractory focal epilepsy (20212642)…

Investigator
Katherine Zarroli
IRB Number
1332866
Location
Jacksonville

A double-blind, randomized, placebo-controlled, multicenter, outpatient, parallel-group study to assess the efficacy and safety of staccato alprazolam in study participants 12 years of age and older with stereotypical prolonged seizures (20216831)

A double-blind, randomized, placebo-controlled, multicenter, outpatient, parallel-group study to assess the efficacy and safety of staccato alprazolam in study participants 12 years of age and older…

Investigator
Suparna Krishnaiengar
IRB Number
1324323
Location
Jacksonville

An open-label, multicenter, outpatient extension study to evaluate the safety and tolerability of staccato alprazolam in study participants 12 years of age and older with stereotypical prolonged seizures (20216843)

An open-label, multicenter, outpatient extension study to evaluate the safety and tolerability of staccato alprazolam in study participants 12 years of age and older with stereotypical prolonged…

Investigator
Suparna Krishnaiengar
IRB Number
1324368
Location
Jacksonville