William R Frazier, M.D., Ph.D.

William Frazier, MD, is a neurologist and neuroimmunologist appointed as an assistant professor in the Department of Neurology at the University of Florida College of Medicine – Jacksonville.

Dr. Frazier specializes in the diagnosis and treatment of autoimmune, inflammatory and infectious disorders of the central nervous system. His clinical practice includes the care of patients with multiple sclerosis, autoimmune encephalitis, HTLV-1–associated myelopathy/tropical spastic paraparesis (HAM/TSP), MOG antibody–associated disease (MOGAD), neuromyelitis optica spectrum disorder (NMOSD), paraneoplastic neurological syndromes, transverse myelitis, and other complex neuroimmune and neuroinfectious conditions.

His philosophy of care emphasizes patient education and shared decision-making, helping patients understand their conditions and actively participate in treatment planning.

Dr. Frazier earned his medical degree and doctor of philosophy from Georgetown University School of Medicine, completed neurology residency through the MedStar Georgetown–NIH Neurology Program, and completed fellowship training in neuroimmunology and neurovirology at the National Institute of Neurological Disorders and Stroke (NINDS), National Institutes of Health.

His research focuses on improving the diagnosis, prognostication and treatment of autoimmune diseases that affect the central nervous system. He is also interested in translational studies aimed at preventing neuroimmune injury and restoring function in affected patients.